ZD0947

CAT: 0804-HY-120158Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-120158Size:1 Each

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

ZD0947 is an ATP-sensitive potassium channel activator with relatively effective activation of smooth muscle KATP channels (SUR2B/Kir6.1 and SUR2B/Kir6.2) . ZD0947 partially antagonizes pancreatic KATP channels (SUR1/Kir6.2) and cardiac KATP channels (SUR2A/Kir6.2) . ZD0947 is potentially used to inhibit overactive bladder (OAB) [1].

CAS Number

172649-40-0

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/zd0947.html

Smiles

N#CC1=CC=CC([C@@H]2C=C(NC3=C2C(CCC3)=O)C(F)(F)F)=C1

Molecular Formula

C17H13F3N2O

Molecular Weight

318.29

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Effects of ZD0947, a novel and potent ATP-sensitive K+ channel opener, on smooth muscle-type ATP-sensitive K+ channels

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 2

ZD0947

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