Evifacotrep

• Description :

  Evifacotrep, a short transient receptor potential channel 5 and 4 (TRPC5/TRPC4) antagonist (WO2020061162, compound 100), can be used for the research of neurological diseases. Evifacotrep targets to TRPC5/TRPC4 with IC50s ≤50 nM[1].

• CAS Number :

  [2413739-88-3]

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319

• Target :

  TRP Channel

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/evifacotrep.html

• Purity :

  99.65

• Solubility :

  DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  O=C1NN=CC(N2CC3=C(CC2)C(OC4=CC=C(C=C4C(F)(F)F)F)=NC=N3)=C1Cl

• Molecular Formula :

  C18H12ClF4N5O2

• Molecular Weight :

  441.77

• Precautions :

  H302, H315, H319

• References & Citations :

  [1]WO2020061162

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported