Monoolein

• Description:

  Monoolein is a biocompatible lipid molecule that can be used as a carrier for bone repair. Monoolein exhibits anti-inflammatory activity by inhibiting the immune response induced by LPS (HY-D1056) . It exerts its anti-inflammatory effects by reducing the production of immune response factors such as IL-12 p40, IL-6, and TNF-α, and inhibiting the generation of NO. Monoolein can be used in drug delivery and research in the field of inflammatory diseases [1][2].

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Endogenous Metabolite; Interleukin Related; NO Synthase; TNF Receptor

• Type:

  Natural Products

• Related Pathways:

  Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/monoolein.html

• Purity:

  99.91

• Solubility:

  Ethanol : 100 mg/mL (ultrasonic)

• Smiles:

  CCCCCCCC/C=C\CCCCCCCC(OCC(O)CO)=O

• Molecular Formula:

  C21H40O4

• Molecular Weight:

  356.54

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Ali I, et al. Monoolein, isolated from Ishige sinicola, inhibits lipopolysaccharide-induced inflammatory response by attenuating mitogen-activated protein kinase and NF-κB pathways. Food Sci Biotechnol. 2017 Apr 30;26 (2) :507-511.|[2]Issa JP, et al. Monoolein and chitosan gels as potential carriers of the rhBMP-2, using decortication surgical technique in Wistar rats as experimental model. Micron. 2008 Oct;39 (7) :952-9.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• Isoform:

  Human Endogenous Metabolite

• CAS Number:

  [111-03-5]