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1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one

CAT:
804-HY-N0998
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one - image 1

1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one

  • UNSPSC Description:

    1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one (compound 6) shows antiproliferative activity with ED50s of 57.7, 78.8 μM for 26-L5 and HT-1080 cells, respectively. 1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one inhibits melanogenesis in B16 melanoma 4A5 cells. 1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one has the potential for the research of skin disorders[1][2].

  • Target Antigen:

    Others

  • Type:

    Natural Products

  • Related Pathways:

    Others

  • Applications:

    Cancer-programmed cell death

  • Field of Research:

    Cancer

  • Assay Protocol:

    https://www.medchemexpress.com/1-7-bis-4-hydroxyphenyl-hepta-4e-6e-dien-3-one.html

  • Solubility:

    10 mM in DMSO

  • Smiles:

    O=C(/C=C/C=C/C1=CC=C(O)C=C1)CCC2=CC=C(O)C=C2

  • Molecular Weight:

    294.34

  • References & Citations:

    [1]Ali MS, et al. Six new diarylheptanoids from the seeds of Alpinia blepharocalyx. J Nat Prod. 2001 Mar;64(3):289-93.|[2]Matsumoto T, et al. Diarylheptanoids with inhibitory effects on melanogenesis from the rhizomes of Curcuma comosa in B16 melanoma cells. Bioorg Med Chem Lett. 2013 Sep 15;23(18):5178-81.

  • Shipping Conditions:

    Room temperature

  • Clinical Information:

    No Development Reported

  • CAS Number:

    332371-82-1

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