Cl-NQTrp
CAT:
804-HY-138643-03
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Cl-NQTrp
- CAS Number: 185351-23-9
- UNSPSC Description: Cl-NQTrp signifcantly disrupts the preformed fbrillar aggregates of Tau-derived PHF6 (VQIVYK) peptide and full-length tau protein[1][2].
- Target Antigen: Amyloid-β
- Type: Reference compound
- Related Pathways: Neuronal Signaling
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/cl-nqtrp.html
- Smiles: ClC(C(C1=C(C=CC=C1)C2=O)=O)=C2N[C@H](C(O)=O)CC3=CNC4=C3C=CC=C4
- Molecular Weight: 394.81
- References & Citations: [1]V Guru KrishnaKumar, et al. Mechanistic insights into remodeled Tau-derived PHF6 peptide fibrils by Naphthoquinone-Tryptophan hybrids. Sci Rep. 2018 Jan 8;8(1):71.|[2]Moran Frenkel-Pinter, et al. Cl-NQTrp Alleviates Tauopathy Symptoms in a Model Organism through the Inhibition of Tau Aggregation-Engendered Toxicity. Neurodegener Dis. 2017;17(2-3):73-82.
- Shipping Conditions: Blue Ice