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Diphenyl Phosphate

CAT: 0804-HY-W008151-01Size: 5 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W008151-01Size:5 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Diphenyl Phosphate inhibits growth and energy metabolism in zebrafish and mice in a sex-specific manner. Diphenyl Phosphate can inhibit the activity of SDH (respiratory complex II), reduce the expression of CPT1 and disrupts the integrity of the mitochondrial membrane. Diphenyl Phosphate may be used in research on metabolic diseases[1][2].
CAS Number
838-85-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Mitochondrial Metabolism
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/diphenyl-phosphate.html
Purity
99.98
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=P(OC1=CC=CC=C1)(OC2=CC=CC=C2)O
Molecular Formula
C12H11O4P
Molecular Weight
250.19
Precautions
H302, H315, H319, H335
References & Citations
[1]Chen Q, et al. Life Cycle Exposure to Environmentally Relevant Concentrations of Diphenyl Phosphate (DPhP) Inhibits Growth and Energy Metabolism of Zebrafish in a Sex-Specific Manner. Environ Sci Technol. 2021 Oct 5;55 (19) :13122-13131. |[2]Wang D, et al. Neonatal triphenyl phosphate and its metabolite diphenyl phosphate exposure induce sex- and dose-dependent metabolic disruptions in adult mice. Environ Pollut. 2018 Jun;237:10-17.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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