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Dalfopristin

CAT: 0804-HY-A0241-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-A0241-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dalfopristin (RP54476) is a semisynthetic sulfone antibiotic. Dalfopristin alone has limited antibacterial activity, but synergistically with Quinupristin it has significant bactericidal activity against many pathogenic Gram-positive cocci[1].
CAS Number
112362-50-2
Product Name Alternative
RP54476
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Dalfopristin.html
Concentration
10mM
Purity
99.67
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=S(CCN(CC)CC)([C@H]1[C@@](C(O[C@H]([C@@H](/C=C/C(NC/C=C\C(C)=C\2)=O)C)C(C)C)=O)([H])N(C(C3=COC(CC(C[C@@H]2O)=O)=N3)=O)CC1)=O
Molecular Formula
C34H50N4O9S
Molecular Weight
690.85
Precautions
H315, H319, H320
References & Citations
[1]A Le Liboux, et al. Simultaneous high-performance liquid chromatographic determination of quinupristin, dalfopristin and their main metabolites in human plasma. J Chromatogr B Biomed Sci Appl. 1998 Apr 24;708 (1-2) :161-8. |[2]Martinet MR, et al. Lack of effect of streptogramins on hepatic drug metabolism enzymes in the rat. Drug Metab Dispos. 1992 Jul-Aug;20 (4) :490-5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched