1,2-O-Isopropylidene-5-O-p-toluoyl-a-D-xylofuranose

1,2-O-Isopropylidene-5-O-p-toluoyl-a-D-xylofuranose

• CAS Number: 75096-60-5
• UNSPSC Description: 1,2-O-Isopropylidene-5-O-p-toluoyl-a-D-xylofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/1-2-o-isopropylidene-5-o-p-toluoyl-a-d-xylofuranose.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@@H]1[C@]2([H])[C@](OC(C)(O2)C)([H])O[C@@H]1COC(C3=CC=C(C=C3)C)=O
• Molecular Weight: 308.33
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported