Methoxyflurane

CAT: 804-HY-B0718-01Size: 100 mgDry Ice: NoHazardous: No
100 mgSelected
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Methoxyflurane disrupts neuronal transmission by interfering with the release and re-uptake of neurotransmitters at post-synaptic terminals, or altering ionic conductance following receptor activation[1]. Methoxyflurane is an analgesic agent that provides rapid short-term analgesia. Methoxyflurane may shows a effective non-opioid treatment option for trauma pain[2].
CAS Number
[76-38-0]
Product Name Alternative
DA-759
UNSPSC
12352211
Hazard Statement
H226-H319-H341
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/methoxyflurane.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
COC(F)(F)C(Cl)Cl
Molecular Formula
C3H4Cl2F2O
Molecular Weight
164.97
Precautions
P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P405-P501
References & Citations
[1]Mercadante S, et al. Analgesic Efficacy, Practicality and Safety of Inhaled Methoxyflurane Versus Standard Analgesic Treatment for Acute Trauma Pain in the Emergency Setting: A Randomised, Open-Label, Active-Controlled, Multicentre Trial in Italy (MEDITA) .Adv Ther. 2019 Nov;36 (11) :3030-3046.|[2]NCI Drug Dictionary.methoxyflurane
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

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