Hydralazine-d4 (hydrochloride)

Hydralazine-d4 (hydrochloride)

• CAS Number: 2749234-32-8
• UNSPSC Description: Hydralazine-d4 hydrochloride is the deuterium labeled Hydralazine hydrochloride. Hydralazine hydrochloride is a direct-acting vasodilator that is used as an antihypertensive agent.
• Target Antigen: HIF/HIF Prolyl-Hydroxylase; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease;Others
• Field of Research: Cardiovascular Disease
• Solubility: 10 mM in DMSO
• Smiles: N/N=C1C2=C(C([2H])=C([2H])C([2H])=C2[2H])C=NN/1.Cl
• Molecular Weight: 200.66
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Bourreli, B., et al., Additive effects of dihydralazine during enflurane or isoflurane hypotensive anaesthesia for spinal fusion. Can J Anaesth, 1988. 35(3 ( Pt 1)): p. 242-8.|[3]Kandler, M.R., et al., Hydralazine for essential hypertension. Cochrane Database Syst Rev, 2010(8): p. CD004934.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported