CFTR antibody

CAT: 0710-FNab10866Size: 100 µgDry Ice: NoHazardous: No

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CAT#:0710-FNab10866Size:100 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Involved in the transport of chloride ions. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the SLC4A7 transporter. Can inhibit the chloride channel activity of ANO1. Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation.

Synonyms

Gene ID

1080

UniProt

P13569

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)

Target

CFTR

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

168 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB

UniProtKB · P13569

Cystic fibrosis transmembrane conductance regulator

CFTR_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P13569
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: CFTR
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: CFTR
EC number: —
Processing: —
Secondary accessions: Q20BG8, Q20BH2, Q2I0A1, Q2I102

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingChlorideNucleotide-binding

Cellular component

Cell membraneEndoplasmic reticulumEndosomeMembraneNucleus

Molecular function

Chloride channelIon channelIsomerase

Disease

Disease variant

PTM

GlycoproteinIsopeptide bondLipoproteinPalmitatePhosphoproteinUbl conjugation

Biological process

Ion transportTransport

Domain

RepeatTransmembraneTransmembrane helix

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Alternative Products

Catalog	Name
33-786	CFTR Antibody [CFTR/1785]
33-777	CFTR Antibody [CFTR/1643]
33-773	CFTR Antibody [CFTR/1341]
33-787	Recombinant CFTR Antibody [CFTR/1775R]
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