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Wilforgine

CAT: 0804-HY-N1072-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N1072-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Wilforgine is a bioactive sesquiterpene alkaloid in Tripterygium wilfordii Hook. F. Wilforgine can induce microstructural and ultrastructural changes in the muscles of Mythimna separata larvae, and the sites of action are proposed to be calcium receptors or channels in the muscular system[1][2].
CAS Number
37239-47-7
UNSPSC
12352005
Hazard Statement
H302
Target
Calcium Channel
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/wilforgine.html
Purity
99.67
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C)OCC(C1OC(C)=O)(C(C(OC(C2=COC=C2)=O)C3OC(C4C)=O)OC(C)=O)C(OC(C)(COC(C(C=CC=N5)=C5CC4)=O)C6C1OC(C)=O)(C3(O)C)C6OC(C)=O
Molecular Formula
C41H47NO19
Molecular Weight
857.81
Precautions
H302
References & Citations
[1]Ouyang XK, et al. Simultaneous determination of four sesquiterpene alkaloids in Tripterygium wilfordii Hook. F. extracts by high-performance liquid chromatography. Phytochem Anal. 2007 Jul-Aug;18 (4) :320-5.|[2]Ma S, et al. Comparative studies on muscle microstructure and ultrastructure of Mythimna separata Walker treated with wilforgine and chlorantraniliprole. Ecotoxicol Environ Saf. 2018 Jan;147:1023-1034.|[3]Gao X, et al. Wilforine, the Q-marker and PK-maker of Tripterygium glycosides tablet: Based on preparation quantitative analysis and PK-PD study. Phytomedicine. 2019 Feb 15;54:357-364.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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