2,3-Diphosphoglyceric acid (pentasodium)

• UNSPSC Description:

  2,3-Diphosphoglyceric acid (2,3-DPG) pentasodium is an intermediate of the glycolytic pathway. 2,3-Diphosphoglyceric acid pentasodium stabilizes the deoxygenated form of hemoglobin by allosteric binding and facilitates oxygen release at tissue sites. 2,3-Diphosphoglyceric acid pentasodium binds to hemoglobin and decrease its affinity for oxygen[1][2].

• Target Antigen:

  Parasite

• Type:

  Natural Products

• Related Pathways:

  Anti-infection

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/2-3-diphosphoglyceric-acid-pentasodium.html

• Purity:

  98.0

• Solubility:

  DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 250 mg/mL (ultrasonic)

• Smiles:

  O=C(O[Na])C(OP(O[Na])(O[Na])=O)COP(O[Na])(O[Na])=O

• Molecular Weight:

  375.95

• References & Citations:

  [1]Shakil H. Merchant MD, et al. 24 - Molecular Diagnosis in Hematopathology. Hematopathology (Second Edition).2012, 679-726. |[2]Płoszczyca K, et al. Red Blood Cell 2,3-Diphosphoglycerate Decreases in Response to a 30 km Time Trial Under Hypoxia in Cyclists. Front Physiol. 2021 Jun 15;12:670977.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, stored under nitrogen, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  1287756-01-7