Tyloxapol

Tyloxapol

• CAS Number: 25301-02-4
• UNSPSC Description: Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type, used as a surface active stabilizer. Tyloxapol is used to induce hyperlipidemia in animals[1][2].
• Target Antigen: Biochemical Assay Reagents
• Type: Reference compound
• Related Pathways: Others
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/Tyloxapol.html
• Solubility: DMSO : ≥ 38 mg/mL|Ethanol : 100 mg/mL (ultrasonic)|H2O : 120 mg/mL (ultrasonic)
• Smiles: [H]OCCOC1=C(CC)C=C(C(CC(C)(C)C)(C)C)C=C1C.[6].[=].[<].[5].[8].[n].[m].[_].[=].[m].[n]
• Molecular Weight: 261.38 (monomer)
• References & Citations: [1]Heba Mohamed Abdou, et al. The Journal of Basic and Applied Zoology volume 79, Article number: 51 (2018).|[2]de Sousa JA, et al. Evaluation of DNA damage in Wistar rat tissues with hyperlipidemia induced by tyloxapol. Exp Mol Pathol. 2017 Aug;103(1):51-55.|[3]Julijana Kristl, et al. Surface active stabilizer tyloxapol in colloidal dispersions exerts cytostatic effects and apoptotic dismissal of cells. Toxicol Appl Pharmacol. 2008 Oct 15;232(2):218-25.|[4]Kuroda M, et al. Biochim Biophys Acta. 1977 Oct 24;489(1):119-25.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light)
• Clinical Information: Launched