Tyloxapol

• Description :

  Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type, used as a surface active stabilizer. Tyloxapol is used to induce hyperlipidemia in animals[1][2].

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319, H335

• Target :

  Biochemical Assay Reagents

• Type :

  Reference compound

• Related Pathways :

  Others

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/Tyloxapol.html

• Purity :

  0

• Solubility :

  DMSO : ≥ 38 mg/mL|Ethanol : 100 mg/mL (ultrasonic) |H2O : 120 mg/mL (ultrasonic)

• Smiles :

  [H]OCCOC1=C(CC)C=C(C(CC(C)(C)C)(C)C)C=C1C.[6].[=].[<].[5].[8].[n].[m].[_].[=].[m].[n]

• Molecular Formula :

  (C15H21O (C2H4O) m) n

• Molecular Weight :

  261.38 (monomer)

• Precautions :

  H315, H319, H335

• References & Citations :

  [1]Heba Mohamed Abdou, et al. The Journal of Basic and Applied Zoology volume 79, Article number: 51 (2018) .|[2]de Sousa JA, et al. Evaluation of DNA damage in Wistar rat tissues with hyperlipidemia induced by tyloxapol. Exp Mol Pathol. 2017 Aug;103 (1) :51-55.|[3]Julijana Kristl, et al. Surface active stabilizer tyloxapol in colloidal dispersions exerts cytostatic effects and apoptotic dismissal of cells. Toxicol Appl Pharmacol. 2008 Oct 15;232 (2) :218-25.|[4]Kuroda M, et al. Biochim Biophys Acta. 1977 Oct 24;489 (1) :119-25.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• CAS Number :

  [25301-02-4]