MEK1 Derived Peptide Inhibitor 1

MEK1 Derived Peptide Inhibitor 1

• CAS Number: 355367-87-2
• UNSPSC Description: MEK1 Derived Peptide Inhibitor 1 is a peptide inhibitor. MEK1 Derived Peptide Inhibitor 1 can inhibit the in vitro activation of ERK2 by MEK1 with an IC50 value of 30 μM. MEK1 Derived Peptide Inhibitor 1 can be used for the research of cell-permeable[1].
• Target Antigen: ERK; MEK
• Type: Peptides
• Related Pathways: MAPK/ERK Pathway;Stem Cell/Wnt
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mek1-derived-peptide-inhibitor-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N1[C@@H](CCC1)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N2[C@@H](CCC2)C(N[C@@H]([C@H](O)C)C(N3[C@@H](CCC3)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC(N)=O)C(N4[C@@H](CCC4)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCSC)N
• Molecular Weight: 1491.84
• References & Citations: [1]Bradley R Kelemen, et al. Selective in vivo inhibition of mitogen-activated protein kinase activation using cell-permeable peptides. J Biol Chem. 2002 Mar 8;277(10):8741-8.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported