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Urantide

CAT: 0804-HY-108055Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-108055Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Urantide is a selective and competitive urotensin-II (UT) receptor antagonist peptide (pKB=8.3) that blocks human urotensin-II (hU-II) -induced contractions in rat thoracic aorta ex vivo. Urantide can be used to study the (patho) physiological role of hU-II in the mammalian cardiovascular system[1].
CAS Number
669089-53-6
UNSPSC
12352209
Target
Others; Urotensin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/urantide.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](NC([C@H](C(C)(SSC[C@H](NC([C@@H](NC([C@@H](NC1=O)CCCN)=O)CC2=CC=C(C=C2)O)=O)C(N[C@H](C(O)=O)C(C)C)=O)C)NC([C@@H](N)CC(O)=O)=O)=O)CC3=CC=CC=C3)N[C@@H]1CC4=CNC5=CC=CC=C45
Molecular Formula
C51H66N10O12S2
Molecular Weight
1075.26
References & Citations
[1]Patacchini R, et al. Urantide TFA: an ultrapotent urotensin II antagonist peptide in the rat aorta. Br J Pharmacol. 2003 Dec;140 (7) :1155-8.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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