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Gardneramine

CAT: 0804-HY-N3931Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N3931Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Gardneramine is an orally active alkaloid that acts like papaverine. Gardneramine has peripheral vascular diastolic effect, direct inhibition on myocardium and central inhibition. Gardneramine showed antihypertensive, vasodilatation and atrial inhibition effects in rabbit, dog and guinea pig models, respectively. Gardneramine also inhibits the movement of smooth muscle organs such as the stomach and intestines[1].
CAS Number
34274-91-4
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/gardneramine.html
Solubility
10 mM in DMSO
Smiles
COC1=C2C34C5N(C/6)[C@@]([C@](COC4=NC2=C(OC)C=C1OC)([H])[C@@](C6=C\COC)([H])C5)([H])C3
Molecular Formula
C23H28N2O5
Molecular Weight
412.48
References & Citations
[1]Harada M, et al. [Pharmacological studies on gardneria alkaloids. II. Peripheral effects (effects on circulatory and digestive systems) ]. Yakugaku Zasshi. 1972 Dec;92 (12) :1540-6. Japanese.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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CatalogName
TN6028Gardneramine

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