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NLRP3 Human Gene Knockout Kit (CRISPR)

CAT: 0937-KN213623Size: 1 KitDry Ice: NoHazardous: No
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CAT#:0937-KN213623Size:1 Kit
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NLRP3 - human gene knockout kit via CRISPR, HDR mediated
UniProt
Q96P20
Gene Location
114548
Symbol
NLRP3

UniProtKB · Q96P20

NACHT, LRR and PYD domains-containing protein 3

NLRP3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q96P20
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NLRP3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.6.4.-
Processing
—
Secondary accessions
A0A024R5Q0, B2RC97, B7ZKS9, B7ZKT2, B7ZKT3, O75434, Q17RS2, Q59H68, Q5JQS8, Q5JQS9, Q6TG35, Q8TCW0, Q8TEU9, Q8WXH9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorHydrolase

PTM

ADP-ribosylationDisulfide bondIsopeptide bondLipoproteinPalmitatePhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Disease

AmyloidosisDeafnessDisease variantNon-syndromic deafness

Ligand

ATP-bindingNucleotide-binding

Cellular component

CytoplasmCytoskeletonEndoplasmic reticulumGolgi apparatusInflammasomeMembraneMitochondrionNucleusSecreted

Biological process

ImmunityInflammatory responseInnate immunityTranscriptionTranscription regulation

Domain

Leucine-rich repeatRepeat

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