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Columbianadin

CAT: 0804-HY-N0362-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0362-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Columbianadin, a natural coumarin from Heracleum hemsleyanum, is known to have various biological activities including anti-inflammatory and anti-cancer effects.
CAS Number
5058-13-9
UNSPSC
12352005
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Columbianadin.html
Purity
99.92
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C/C=C(C)\C(OC(C)([C@@H]1CC2=C(O3)C(C=CC3=O)=CC=C2O1)C)=O
Molecular Formula
C19H20O5
Molecular Weight
328.36
References & Citations
[1]Kang JI, et al. Columbianadin Inhibits Cell Proliferation by Inducing Apoptosis and Necroptosis in HCT116 Colon Cancer Cells. Biomol Ther (Seoul) . 2016 May 1;24 (3) :320-7.|[2]Zhang YB, et al. Tissue distribution study of columbianadin and its active metabolite columbianetin in rats. Biomed Chromatogr. 2016 Feb;30 (2) :256-62.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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N2424-20Columbianadin
A14763-10Columbianadin 10mg
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