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Biliatresone

CAT: 0804-HY-119412-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-119412-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Biliatresone is a natural toxin isolated from Dysphania glomulifera and D. littoralis. Biliatresone, a 1,2-diaryl-2-propenone class of isoflavonoid, produces extrahepatic biliary atresia in a zebrafish model[1].
CAS Number
1801433-90-8
UNSPSC
12352005
Hazard Statement
H300
Target
Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/biliatresone.html
Purity
99.48
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
C=C(C(C1=C(C=C2OCOC2=C1OC)OC)=O)C3=CC=CC=C3O
Molecular Formula
C18H16O6
Molecular Weight
328.32
Precautions
H300
References & Citations
[1]Kyung A Koo, et al. Biliatresone, a Reactive Natural Toxin From Dysphania Glomulifera and D. Littoralis: Discovery of the Toxic Moiety 1,2-Diaryl-2-Propenone. Chem Res Toxicol. 2015 Aug 17;28 (8) :1519-21.|[2]Kristin Lorent, et al. Identification of a Plant Isoflavonoid That Causes Biliary Atresia. Sci Transl Med. 2015 May 6;7 (286) :286ra67.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C, stored under nitrogen
Scientific Category
Natural Products
Clinical Information
No Development Reported

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