MSP-3

• Description :

  MSP-3 is a potent TRPV1 agonist, with an EC50 of 0.87 μM. MSP-3 exhibits neuroprotective and antinociceptive effects[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319, H401

• Target :

  TRP Channel

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/msp-3.html

• Purity :

  98.53

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(CCCC1=CC=CS1)NCC2=CC=C(C(OC)=C2)O

• Molecular Formula :

  C16H19NO3S

• Molecular Weight :

  305.39

• Precautions :

  H315, H319, H401

• References & Citations :

  [1]Aiello F, et, al. Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N- (4-Hydroxy-3-methoxybenzyl) -4- (thiophen-2-yl) butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress. ACS Chem Neurosci. 2016 Jun 15;7 (6) :737-48.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2

• Isoform :

  TRPV1

• CAS Number :

  [1820968-63-5]