MSP-3

• Description:

  MSP-3 is a potent TRPV1 agonist, with an EC50 of 0.87 μM. MSP-3 exhibits neuroprotective and antinociceptive effects[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H315, H319, H401

• Target:

  TRP Channel

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/msp-3.html

• Purity:

  98.53

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C (CCCC1=CC=CS1) NCC2=CC=C (C (OC) =C2) O

• Molecular Formula:

  C16H19NO3S

• Molecular Weight:

  305.39

• Precautions:

  H315, H319, H401

• References & Citations:

  [1]Aiello F, et, al. Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N- (4-Hydroxy-3-methoxybenzyl) -4- (thiophen-2-yl) butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress. ACS Chem Neurosci. 2016 Jun 15;7 (6) :737-48.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 2

• Isoform:

  TRPV1

• CAS Number:

  1820968-63-5