Azido-PEG3-NHS ester

CAT:

804-HY-140764-03

Size:

250 mg

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CAS Number: 1092654-47-1
UNSPSC Description: Azido-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Target Antigen: PROTAC Linkers
Type: Reference compound
Related Pathways: PROTAC
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/azido-peg3-nhs-ester.html
Solubility: Ethanol : 50 mg/mL (ultrasonic)
Smiles: O=C(ON1C(CCC1=O)=O)COCCOCCOCCN=[N+]=[N-]
Molecular Weight: 330.29
References & Citations: [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions: Blue Ice
Clinical Information: No Development Reported

Cat	Name
HY-140764-03	Azido-PEG3-NHS ester
HY-140764-01	Azido-PEG3-NHS ester
HY-140764-02	Azido-PEG3-NHS ester
HY-140768	Azido-PEG3-O-NHS ester
HY-140770	Azido-PEG3-aminoacetic acid-NHS ester
HY-140561	N-(Azido-PEG3)-N-Boc-PEG3-NHS ester
HY-135966-01	Azido-PEG3-SS-NHS
HY-135966-02	Azido-PEG3-SS-NHS
HY-140559-02	N-(Azido-PEG2)-N-Boc-PEG3-NHS ester
HY-140865	2-(Azido-PEG3-amido)-1,3-bis(NHS ester)