Products for Research Use Only
RegisterLogin

Ambamustine

CAT: 0804-HY-19577Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-19577Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Ambamustine (PTT119) is a bifunctional alkylating agent and induces DNA damage by alkylating mechanisms. Ambamustine interferes with late steps in murine mammary tumor virus (MuMTV) processing and maturation and reduces production of the B-type retrovirus MuMTV. Ambamustine possesses cytolytic and antiviral activities[1][2].
CAS Number
85754-59-2
Product Name Alternative
PTT119
UNSPSC
12352005
Target
DNA Alkylator/Crosslinker
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/ambamustine.html
Smiles
CSCC[C@@H](C(OCC)=O)NC([C@H](CC1=CC=CC(N(CCCl)CCCl)=C1)NC([C@H](CC2=CC=C(F)C=C2)N)=O)=O
Molecular Formula
C29H39Cl2FN4O4S
Molecular Weight
629.61
References & Citations
[1]M J Yagi, et al. Interference of mouse mammary tumor virus replication by PTT.119 [p-fluoro-L-phe-m-bis- (2-chloroethyl) amino-L-phe-met ethoxy HCl]--an antitumor agent. J Natl Cancer Inst. 1986 Mar;76 (3) :493-501. |[2]A Ardizzoni, et al. Ambamustine in the second-line treatment of patients with small-cell lung cancer: a phase II Fonicap study. Am J Clin Oncol. 2000 Feb;23 (1) :22-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
GTR19199508-01Ambamustine
MBS5774817Ambamustine HCl

Popular Products