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TLR2 Rabbit Polyclonal Antibody

CAT: 0013-GTR17722990-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0013-GTR17722990-01Size:50 μL
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Description
TLR2 Rabbit Polyclonal Antibody
Product Name Alternative
CD282; TIL4; TLR2_HUMAN; TLR2; Toll/interleukin-1 receptor-like protein 4; toll like receptor 2; toll-like receptor 2
UniProt
O60603
Reactivity
Human, Mouse
Immunogen
KLH conjugated synthetic peptide derived from human TLR2 (1-600/784aa)
Target
TLR2
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Affinity purified by Protein A
Concentration
1mg/ml
Dilution
WB=1:500-2000, Flow-Cyt=1μg/Test
Form
Liquid
Molecular Weight
100 kDa
References & Citations
Ezz, Mohamed Aboul et al. TLR2/4 signaling pathway mediates sperm-induced inflammation in bovine endometrial epithelial cells in vitro PLoS ONE, 14, e0214516 (2019), Bishayi, B. et al. Possible role of Toll-like receptor-2 in the intracellular survival of Staphylococcus aureus in murine peritoneal macrophages: involvement of cytokines and anti-oxidant enzymes Scand J Immunol, 80, 127-143 (2014), Kowsar, Rasoul et al. Regulation of innate immune function in bovine oviduct epithelial cells in culture: the homeostatic role of epithelial cells in balancing Th1/Th2 response J Reprod Dev, 59, 470-478 (2013), Rituparna Ghosh 1, Biswadev Bishayi Neutralization of TLR2 in combination with either TNF-α or IL-1β antibody reduces the severity of septic arthritis through STAT3/mTOR signalling in lymphocytes Cell Immunol ., (2024), I Akthar, Y Kim, T Umehara, C Kanno Activation of sperm Toll-like receptor 2 induces hyperactivation to enhance the penetration to mucus and uterine glands: a trigger for the uterine inflammatory cascade Frontiers in Immunology, (2024), Ajeya Nandi, Biswadev Bishayi A novel CCR-2/TLR-2 triggered signaling in murine peritoneal macrophages intensifies bacterial (Staphylococcus aureus) killing by reactive oxygen species through TNF-R1 Immunology Letters, 190, (2017), Rituparna Ghosh 1, Biswadev Bishayi Endogenous blocking of TLR2 along with TNF-α and IL-1β ameliorates the severity of the S. aureus arthritis via modulating STAT3/SOCS3 expressions in tissue resident macrophages Microb Pathog, (2024), Malinda Hulugalla 1, Alireza Mansouri 1, Elham Waehama 1 2, Ihshan Akthar 1, Akio Miyamoto Semen extender triggers a mild physiological inflammatory response in the uterus without disrupting sperm-uterine immune crosstalk in vitro in cattle J Reprod Dev, (2024), Dongxue Ma 1, Ihshan Akthar 1, Taiyo Hashimoto 1, Mohamed A Marey 1 2, Kazuya Kusama 3, Kazuhiko Imakawa 4, Masayuki Shimada 5, Akio Miyamoto Toll-like receptor 2 activation of early divided bovine embryo promotes its viability and development competence in vitro Sci Rep, (2025), Effects of Bdellovibrio bacteriovorus HD100 on experimental periodontitis in rats Mol Oral Microbiol, 38, 158-170 (2023), Elham WAEHAMA A diversity of uterine immune response to peptidoglycans (PGNs) derived from different bacterial species in cattle Obihiro University of Agriculture and Veterinary Medicine, (2025), Dey, Rajen et al. Ascorbic acid along with ciprofloxacin regulates S. aureus induced microglial inflammatory responses and oxidative stress through TLR-2 and glucocorticoid receptor modulation Inflammopharmacology, 30, 1303-1322 (2022)
Pubmed id
30995239, 24846691, 23800958, 39312873, 28736159, 38160988, 39647914, 40634450, 36495122, 35704229
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, WB
Host or Source
Rabbit
Preservative
0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
Isotype
IgG

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