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Glucose oxidase

CAT: 0804-HY-P2902-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P2902-01Size:5 mg
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Description
Glucose oxidase is used in the food and beverage industry as a preservative and stabilizer and is commonly derived from the fungus Aspergillus niger. Glucose oxidase can react with intracellular glucose and oxygen (O2) to produce hydrogen peroxide (H2O2) and gluconic acid, which can cut off the nutrition source of cancer cells and consequently inhibit their proliferation[1][2][3].
CAS Number
9001-37-0
UNSPSC
12352204
Hazard Statement
H334
Target
Endogenous Metabolite
Type
Enzyme
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/glucose-oxidase.html
Purity
0
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
[Glucoseoxidase]
Precautions
H334
References & Citations
[1]Konishi T, et al. Safety evaluation of glucose oxidase from Penicillium chrysogenum [published correction appears in Regul Toxicol Pharmacol. 2013 Aug;66 (3) :300]. Regul Toxicol Pharmacol. 2013;66 (1) :13-23. |[2]Leskovac V, et al. Glucose oxidase from Aspergillus niger: the mechanism of action with molecular oxygen, quinones, and one-electron acceptors. Int J Biochem Cell Biol. 2005;37 (4) :731-750. |[3]Wang M, et al. Recent Advances in Glucose-Oxidase-Based Nanocomposites for Tumor Therapy. Small. 2019;15 (51) :e1903895. |[4]Khatami SH, et al. Glucose oxidase: Applications, sources, and recombinant production [published online ahead of print, 2021 Apr 11]. Biotechnol Appl Biochem. 2021;10.1002/bab.2165.
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20°C for 2 years
Scientific Category
Enzyme
Clinical Information
No Development Reported
Isoform
Microbial Metabolite

Chemical Information

Beta-D-Glucose

Beta-D-glucose is D-Glucopyranose with beta configuration at the anomeric centre. It has a role as an epitope and a mouse metabolite. It is an enantiomer of a beta-L-glucose.

CAS Number9001-37-0
PubChem CID64689
IUPAC Name(2R,3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol
Molecular FormulaC6H12O6
Molecular Weight180.16
XLogP-2.6
Topological Polar Surface Area110
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count6
Rotatable Bond Count1
Heavy Atom Count12
Formal Charge0
Complexity151
SMILES
C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
InChI
InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1
InChIKey
WQZGKKKJIJFFOK-VFUOTHLCSA-N
Chemical Structure
2D Structure
2D structure of Beta-D-Glucose
CAS: 9001-37-0
CID: 64689
Formula: C6H12O6
MW: 180.16
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight180.16
XLogP3-2.6
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count6
Rotatable Bond Count1
Exact Mass180.06338810
Monoisotopic Mass180.06338810
Topological Polar Surface Area110 Ų
Heavy Atom Count12
Formal Charge0
Complexity151
Isotope Atom Count0
Defined Atom Stereocenter Count5
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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