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Puromycin

CAT: 0543-P097-25MGSize: 25 mgDry Ice: NoHazardous: No
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CAT#:0543-P097-25MGSize:25 mg
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CAS Number
53-79-2
Applications
Microbiology, Plant Biology.
Purity
>95% by HPLC
Molecular Formula
C22H29N7O5
Molecular Weight
471.5
Shipping Conditions
Ambient
Storage Conditions
-20°C

Chemical Information

Puromycin

Puromycin is an aminonucleoside antibiotic, derived from the Streptomyces alboniger bacterium, that causes premature chain termination during translation taking place in the ribosome. It has a role as a nucleoside antibiotic, an antimicrobial agent, an antiinfective agent, an antineoplastic agent, a protein synthesis inhibitor, an EC 3.4.11.14 (cytosol alanyl aminopeptidase) inhibitor and an EC 3.4.14.2 (dipeptidyl-peptidase II) inhibitor. It is a conjugate base of a puromycin(1+).

CAS Number53-79-2
PubChem CID439530
IUPAC Name(2S)-2-amino-N-[(2S,3S,4R,5R)-5-[6-(dimethylamino)purin-9-yl]-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]-3-(4-methoxyphenyl)propanamide
Molecular FormulaC22H29N7O5
Molecular Weight471.5
XLogP0
Topological Polar Surface Area161
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count10
Rotatable Bond Count8
Heavy Atom Count34
Formal Charge0
Complexity680
SMILES
CN(C)C1=NC=NC2=C1N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)NC(=O)[C@H](CC4=CC=C(C=C4)OC)N)O
InChI
InChI=1S/C22H29N7O5/c1-28(2)19-17-20(25-10-24-19)29(11-26-17)22-18(31)16(15(9-30)34-22)27-21(32)14(23)8-12-4-6-13(33-3)7-5-12/h4-7,10-11,14-16,18,22,30-31H,8-9,23H2,1-3H3,(H,27,32)/t14-,15+,16+,18+,22+/m0/s1
InChIKey
RXWNCPJZOCPEPQ-NVWDDTSBSA-N
Chemical Structure
2D Structure
2D structure of Puromycin
CAS: 53-79-2
CID: 439530
Formula: C22H29N7O5
MW: 471.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight471.5
XLogP30
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count10
Rotatable Bond Count8
Exact Mass471.22301705
Monoisotopic Mass471.22301705
Topological Polar Surface Area161 Ų
Heavy Atom Count34
Formal Charge0
Complexity680
Isotope Atom Count0
Defined Atom Stereocenter Count5
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
abx704706-01Puromycin
41610040-1Puromycin Dihydrochloride
AAA05379Puromycin-D3

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