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Framycetin sulfate

CAT: 0543-F017-500MGSize: 500 mgDry Ice: NoHazardous: No
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CAT#:0543-F017-500MGSize:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
4146-30-9
Applications
Cell Culture, Microbiology, Plant Biology.
Purity
≥ 640 lU/mg
Molecular Formula
C23H48N6O17S
Molecular Weight
712.72
Shipping Conditions
Ambient
Storage Conditions
-20°C

Chemical Information

neomycin b, sulfate (1:3) (salt)

Framycetin Sulfate is the sulfate salt form of framycetin, an aminoglycoside antibiotic isolated from Streptomyces lavendulae (decaris), mainly containing neomycin B, with broad-spectrum antibacterial activity. Framycetin is used mostly as a topical preparation and is poorly absorbed. Upon parenteral administration, this agent can cause nephrotoxicity and ototoxicity.

CAS Number4146-30-9
PubChem CID24978553
IUPAC Name(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol;sulfuric acid
Molecular FormulaC23H52N6O25S3
Molecular Weight908.9
Topological Polar Surface Area602
Hydrogen Bond Donor Count19
Hydrogen Bond Acceptor Count31
Rotatable Bond Count9
Heavy Atom Count57
Formal Charge0
Complexity953
SMILES
C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CN)O)O)N)O[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O[C@@H]4[C@@H]([C@H]([C@@H]([C@@H](O4)CN)O)O)N)O)O)N.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O
InChI
InChI=1S/C23H46N6O13.3H2O4S/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;3*1-5(2,3)4/h5-23,30-36H,1-4,24-29H2;3*(H2,1,2,3,4)/t5-,6+,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;;;/m1.../s1
InChIKey
KWBUARAINLGYMG-JGMIRXPNSA-N
Chemical Structure
2D Structure
2D structure of neomycin b, sulfate (1:3) (salt)
CAS: 4146-30-9
CID: 24978553
Formula: C23H52N6O25S3
MW: 908.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight908.9
Hydrogen Bond Donor Count19
Hydrogen Bond Acceptor Count31
Rotatable Bond Count9
Exact Mass908.21442469
Monoisotopic Mass908.21442469
Topological Polar Surface Area602 Ų
Heavy Atom Count57
Formal Charge0
Complexity953
Isotope Atom Count0
Defined Atom Stereocenter Count19
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count4
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
GA3510-1gFramycetin sulfate
HY-17624A-01Framycetin (sulfate)
HY-17624AR-01Framycetin (sulfate) (Standard)
AR-N01268-01Neomycin B Sulfate (Framycetin Sulfate)
460656-01Neomycin B Trisulfate (Framycetin Sulfate)
RM-F180102-01Framycetin Sulfate EP Impurity B; Neomycin Sulfate EP Impurity B
RM-F180106-01Framycetin Sulfate EP Impurity F; Neomycin Sulfate EP Impurity F
RM-F180104-01Framycetin sulfate EP Impurity D; Neomycin sulfate EP Impurity D
RM-F180105-01Framycetin Sulfate EP Impurity E; Neomycin Sulfate EP Impurity E
RM-F180107-01Framycetin Sulfate EP Impurity G; Neomycin Sulfate EP Impurity G

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