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Hecogenin acetate

CAT: 0804-HY-126941-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-126941-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Hecogenin acetate is a steroidal sapogenin-acetylated with anti-inflammatory and antinociceptive. Hecogenin acetate shows potential antihyperalgesic activity, inhibiting descending pain and acting in opioid receptors[1][2].
CAS Number
915-35-5
UNSPSC
12352005
Target
Opioid Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hecogenin-acetate.html
Purity
98.57
Solubility
THF : 57.5 mg/mL (ultrasonic)
Smiles
[H][C@]1(O[C@@]2(OC[C@H](C)CC2)[C@@H](C)[C@@]1([C@]34C)[H])C[C@@]3([H])[C@]5([H])CC[C@@]6([H])C[C@@H](OC(C)=O)CC[C@]6(C)[C@@]5([H])CC4=O
Molecular Formula
C29H44O5
Molecular Weight
472.66
References & Citations
[1]de França Almeida Moreira CDL, et al. Amorphous solid dispersions of hecogenin acetate using different polymers for enhancement of solubility and improvement of anti-hyperalgesic effect in neuropathic pain model in mice. Biomed Pharmacother. 2018 Jan;97:870-879.|[2]Carvalho YMBG, et al. Inclusion complex between β-cyclodextrin and hecogenin acetate produces superior analgesic effect in animal models for orofacial pain. Biomed Pharmacother. 2017 Sep;93:754-762.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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