Products for Research Use Only

Cryopyrin Rabbit Polyclonal Antibody

CAT: 0013-GTR18102960Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18102960Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cryopyrin Rabbit Polyclonal Antibody is an unconjugated antibody that specifically recognizes Cryopyrin. Generated against a KLH conjugated synthetic peptide derived from human Cryopyrin. The peptide is available as orb374803. The suitable applications for this antibody are IHC-P.
Product Name Alternative
Anti AGTAVPRL antibody, anti C1orf7 antibody, anti Caterpiller protein 1.1 antibody, anti CIAS 1 antibody, anti CIAS1 antibody, anti FCAS antibody, anti FCU antibody, anti MWS antibody, anti NACHT antibody, anti NALP3 antibody, anti NALP 3 antibody, anti NALP-3 antibody, anti NLRP3 antibody, anti PYPAF 1 antibody, anti PYPAF1 antibody, anti PYRIN containing APAF1 like protein 1 antibody
UniProt
Q8R4B8, Q96P20
Immunogen
KLH conjugated synthetic peptide derived from human Cryopyrin. Please contact us for the exact immunogen sequence. The peptide is available as orb374803.
Target
Cryopyrin
Clonality
Polyclonal
Conjugation
Unconjugated
Concentration
- 100 μg (in 200 μl) : 0.5 mg/ml- 200 μg (in 400 μl) : 0.5 mg/ml
Dilution
IHC-P: 1:100-1:500
Purity
Polyclonal antibodies are purified by peptide affinity chromatography
Form
10 mM PBS, 0.02% sodium azide
Molecular Weight
118 kDa
References & Citations
He, Wei et al. Microglial NLRP3 inflammasome activation mediates IL-1β release and contributes to central sensitization in a recurrent nitroglycerin-induced migraine model J Neuroinflammation, 16, 78 (2019), Wilson, C. Brad et al. Valproic acid effects in the hippocampus and prefrontal cortex in an animal model of post-traumatic stress disorder Behav Brain Res, 268, 72-80 (2014), He, Xue-Mei et al. Ellagic Acid Protects Dopamine Neurons via Inhibition of NLRP3 Inflammasome Activation in Microglia Oxid Med Cell Longev, 2020, 2963540 (2020), Wilson, C. Brad et al. Inflammation and oxidative stress are elevated in the brain, blood, and adrenal glands during the progression of post-traumatic stress disorder in a predator exposure animal model PLoS One, 8, e76146 (2013)
Pubmed id
30971286, 24675160, 33294118, 24130763
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
IHC-P
NCBI Accession Number
001073289, 21, 001079821, 11
Host or Source
Rabbit
Isotype
IgG
Entrez
114548