Mlkl Rabbit Polyclonal Antibody

Mlkl Rabbit Polyclonal Antibody is an unconjugated antibody that specifically recognizes Mlkl. Generated against a KLH conjugated synthetic peptide derived from human Mlkl. The peptide is available as orb374793. The suitable applications for this antibody are ICC, IF, IHC-P and WB.

Anti-Mixed lineage kinase domain-like protein antibody, anti-Mlkl antibody

Q8NB16, Q9D2Y4, D3ZKP6

KLH conjugated synthetic peptide derived from human Mlkl. Please contact us for the exact immunogen sequence. The peptide is available as orb374793.

Mlkl

Unconjugated

- 100 μg (in 200 μl) : 0.5 mg/ml- 200 μg (in 400 μl) : 0.5 mg/ml

WB: 1:200-2000, IHC-P: 1:100-500, IF/ICC: 1:100-500

Polyclonal antibodies are purified by peptide affinity chromatography

10 mM PBS, 0.02% sodium azide

54 kDa

Giusy Rita Caponio 1, Alessandro Annunziato 2, Mirco Vacca 2, Graziana Difonzo 2, Giuseppe Celano 2, Fabio Minervini 2, Marianna Ranieri 1, Giovanna Valenti 1, Grazia Tamma 1, Maria De Angelis Nutritional, antioxidant and biological activity characterization of orange peel flour to produce nutraceutical gluten-free muffins Food Funct, (2024), Xing Fan 1, Fang Lin 1, Yu Chen 2, Yuling Dou 1, Ting Li 1 3, Xinxin Jin 4, Jintao Song 2, Fang Wang Luteolin-7- O-β-d-glucuronide Ameliorates Cerebral Ischemic Injury: Involvement of RIP3/MLKL Signaling Pathway Molecules, (2024), Sublethal necroptosis signaling promotes inflammation and liver cancer Immunity, S1074-7613 (23) 00234-0 (2023), Zhang, Liansheng et al. BAD-mediated neuronal apoptosis and neuroinflammation contribute to Alzheimer's disease pathology iScience, 24, 102942 (2021), Günther, Claudia et al. The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitis J Clin Invest, 126, 4346-4360 (2016), Saleh, Danish et al. Chemical Library Screens to Identify Pharmacological Modulators of Necroptosis Methods Mol. Biol., 1857, 19-33 (2018), Zhou, Huiling et al. RIP1/RIP3/MLKL-mediated necroptosis contributes to vinblastine-induced myocardial damage Mol Cell Biochem, 476, 1233-1243 (2021), Fuchslocher Chico, Johaiber et al. The enhanced susceptibility of ADAM-17 hypomorphic mice to DSS-induced colitis is not ameliorated by loss of RIPK3, revealing an unexpected function of ADAM-17 in necroptosis Oncotarget, 9, 12941-12958 (2018), Bittel, Miriam et al. Modulation of the extrinsic cell death signaling pathway by viral Flip induces acute-death mediated liver failure Cell Death Dis, 10, 878 (2019), Choi, Solji et al. 1-Palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol ameliorates chemoradiation-induced oral mucositis Oral Dis, 26, 111-121 (2020), Frank, Tanja et al. Cell cycle arrest in mitosis promotes interferon-induced necroptosis Cell Death Differ, 26, 2046-2060 (2019), Stolberg-Stolberg, Josef et al. Cartilage Trauma Induces Necroptotic Chondrocyte Death and Expulsion of Cellular Contents Int J Mol Sci, 21, 4204 (2020)

39052071, 38611943, 37329888, 34430820, 27756058, 30136227, 33247805, 29560122, 31754092, 31677207, 30742091, 32545631

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

For research use only.

ICC, IF, IHC-P, WB

001142497, 001135969

Rabbit

IgG