CXCR1 Rabbit Polyclonal Antibody

CXCR1 Rabbit Polyclonal Antibody is an unconjugated antibody that specifically recognizes CXCR1. Generated against a KLH conjugated synthetic peptide derived from human CXCR1. The peptide is available as orb12890. The suitable applications for this antibody are ICC, IF, IHC-P and WB.

Q810W6, P70612, P25024

KLH conjugated synthetic peptide derived from human CXCR1. Please contact us for the exact immunogen sequence. The peptide is available as orb12890.

CXCR1

Unconjugated

Immunology & Inflammation

- 100 μg (in 200 μl) : 0.5 mg/ml- 200 μg (in 400 μl) : 0.5 mg/ml

WB: 1:100-800, IHC-P: 1:100-600, IF/ICC: 1:100-600

Polyclonal antibodies are purified by peptide affinity chromatography

10 mM PBS, 0.02% sodium azide

40 kDa

Dutta, Puja et al. Regulation of Staphylococcus aureus-induced CXCR1 expression via inhibition of receptor mobilization and receptor shedding during dual receptor (TNFR1 and IL-1R) neutralization Immunol Res, 67, 241-260 (2019), Dutta, Puja et al. Neutralization of TNF-α and IL-1β Regulates CXCL8 Production through CXCL8/CXCR1 Axis in Macrophages during Staphylococcus aureus Infection Immunol. Invest., (2020), Bishayi, Biswadev et al. Expression of CXCR1 (interleukin-8 receptor) in murine macrophages after staphylococcus aureus infection and its possible implication on intracellular survival correlating with cytokines and bacterial anti-oxidant enzymes Inflammation, 38, 812-827 (2015), Nandi, Ajeya et al. Murine macrophage response from peritoneal cavity requires signals mediated by chemokine receptor CCR-2 during Staphylococcus aureus infection Immunol Res, 64, 213-232 (2016), Ajeya Nandi, Biswadev Bishayi A novel CCR-2/TLR-2 triggered signaling in murine peritoneal macrophages intensifies bacterial (Staphylococcus aureus) killing by reactive oxygen species through TNF-R1 Immunology Letters, 190, (2017), Ajeya Nandi, Biswadev Bishayi CCR-2 neutralization augments murine fresh BMC activation by Staphylococcus aureus via two distinct mechanisms: at the level of ROS production and cytokine response Innate Immunity, 23, 345 (2017)

31290001, 32602757, 25129059, 26616292, 28736159, 28409543

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

For research use only.

ICC, IF, IHC-P, WB

000625

Rabbit

IgG