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BVT173187

CAT: 0804-HY-117971-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-117971-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BVT173187 is a selective inhibitor of the neutrophil formyl peptide receptor FPR1, with activity that inhibits FPR1 activation. BVT173187 inhibits FPR1 agonist-induced activation in neutrophils, reduces adhesion molecule mobilization and superoxide anion production, and has inhibitory activity on FPR1 similar to that of earlier described peptide antagonists, but also has effects on C5aR and CXCR signaling.
CAS Number
1374984-75-4
UNSPSC
12352005
Target
CXCR; Formyl Peptide Receptor (FPR)
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/bvt173187.html
Purity
99.97
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(Cl)=CC(Cl)=C1O)NC2=CC(C)=CC=C2Cl
Molecular Formula
C14H10Cl3NO2
Molecular Weight
330.59
References & Citations
[1]A non-peptide receptor inhibitor with selectivity for one of the neutrophil formyl peptide receptors, FPR 1
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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