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CXM102

CAT: 0804-HY-162866-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-162866-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CXM102 is an autophagy activator. CXM102 can induce autophagy in aged BMSCs, leading to the rejuvenation of BMSCs and preferential differentiation into osteoblasts. CXM102 promotes the nuclear translocation of transcription factor EB (TFEB) and the formation of osteoblasts. CXM102 can stimulate bone synthesis metabolism in middle-aged male mice, reduce bone marrow adipocytes, delay bone loss, lower serum inflammation levels, decrease organ fibrosis, and extend the lifespan of the mice[1].
UNSPSC
12352211
Target
Autophagy
Type
Reference compound
Related Pathways
Autophagy
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/cxm102.html
Purity
99.3600
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=CC(C)=C1C)[C@H]2[C@@H](C(O)=O)C(C3=CC=CC=C3)C=CC2C4=CC=CC=C4
Molecular Formula
C28H27NO3
Molecular Weight
425.52
References & Citations
[1]Luo Z, et al. Rejuvenation of BMSCs senescence by pharmacological enhancement of TFEB-mediated autophagy alleviates aged-related bone loss and extends lifespan in middle aged mice. Bone Res. 2024 Aug 21;12 (1) :45.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
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