5-(Pyridin-4-yl)-1,3,4-oxadiazole-2-thiol

• UNSPSC Description:

  5-(Pyridin-4-yl)-1,3,4-oxadiazole-2-thiol (Compound 3n) is an antimicrobial and antioxidant agent, that inhibits Escherichia coli and Staphylococcus epidermidis, with MIC of 8 and 4 μg/mL. 5-(Pyridin-4-yl)-1,3,4-oxadiazole-2-thiol exhibits antioxidant activity with IC50 of 17.47 μM using DPPH free radical-scavenging method[1].

• Target Antigen:

  Bacterial; Fungal

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Cancer; Infection; Metabolic Disease; Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/5-pyridin-4-yl-1-3-4-oxadiazole-2-thiol.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C1=C(C=CN=C1)C2=NN=C(O2)S

• Molecular Weight:

  179.20

• References & Citations:

  [1]Yarmohammadi E, et al., Ultrasound-assisted, low-solvent and acid/base-free synthesis of 5-substituted 1,3,4-oxadiazole-2-thiols as potent antimicrobial and antioxidant agents. Mol Divers. 2021 Nov;25(4):2367-2378.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  15264-63-8