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Tl45b

CAT: 0804-HY-163861Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163861Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tl45b is an AChE inhibitor, with an IC50 of 0.71 μM. Tl45b can be used for the research of Alzheimer’s disease[1].
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tl45b.html
Smiles
FC(F)(F)C1=CC(C2=CN(CC(NC3=NC4=CC=C(N(CC)NC5)C5=C4S3)=O)N=N2)=CC(C(F)(F)F)=C1
Molecular Formula
C22H17F6N7OS
Molecular Weight
541.47
References & Citations
[1]Fatima Ezzahra Laghchioua, et al. Design of Promising Thiazoloindazole-Based Acetylcholinesterase Inhibitors Guided by Molecular Docking and Experimental Insights. ACS Chem Neurosci. 2024 Jul 22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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CatalogName
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