Trimedoxime

• Description :

  Trimedoxime (TMB-4) is a potent reactivator of AChE. Trimedoxime shows potency in inducing oxidative stress, with the IC50 of 22 mM[1].

• Product Name Alternative :

  TMB-4

• UNSPSC :

  12352005

• Target :

  Cholinesterase (ChE)

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/trimedoxime.html

• Smiles :

  O/N=C/C1=CC=[N+](CCC[N+]2=CC=C(C=C2)/C=N/O)C=C1.[Br-].[Br-]

• Molecular Formula :

  C15H18Br2N4O2

• Molecular Weight :

  446.14

• References & Citations :

  [1]Nela Váňová, et al. In Vitro Evaluation of Oxidative Stress Induced by Oxime Reactivators of Acetylcholinesterase in HepG2 Cells. 2023 Dec 18; 36 (12) : 1912–1920.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [56-97-3]