CD40 Ligand (Human, Recombinant)

• Description:

  CD40 Ligand (Human, Recombinant)_x000D_ Catalog number: B2010347_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Volume/Weight: 10 ug_x000D_ pH: 7.4 upon reconstitution_x000D_ Supplied as: Lyophilized Powder_x000D_ Appearance: Powder_x000D_ Applications: highly pure CD40 Ligand (Human, Recombinant) expressed in E. coli. This protein acts as an important role in immune system regulation, including myeloid progenitor cell development._x000D_ Storage: -20C_x000D_ Keywords: rHuCD40L; CD154; TRAP; TNFSF5; CD40LG; CD40-L_x000D_ Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Kuhn NF, Purdon TJ, van Leeuwen DG, Lopez AV, Curran KJ, Daniyan AF,_x000D_ Brentjens RJ. CD40_Ligand-Modified Chimeric Antigen Receptor T Cells Enhance_x000D_ Antitumor Function by Eliciting an Endogenous Antitumor Response. Cancer Cell._x000D_ 2019 Mar 18;35(3):473-488.e6._x000D_ _x000D_ 2: Karnell JL, Rieder SA, Ettinger R, Kolbeck R. Targeting the CD40-CD40L_x000D_ pathway in autoimmune diseases: Humoral immunity and beyond. Adv Drug Deliv Rev._x000D_ 2019 Feb 15;141:92-103._x000D_ _x000D_ 3: Kawabe T, Matsushima M, Hashimoto N, Imaizumi K, Hasegawa Y. CD40/CD40_ligand_x000D_ interactions in immune responses and pulmonary immunity. Nagoya J Med Sci. 2011_x000D_ Aug;73(3-4):69-78._x000D_ _x000D_ 4: Rizvi M, Pathak D, Freedman JE, Chakrabarti S. CD40-CD40_ligand interactions_x000D_ in oxidative stress, inflammation and vascular disease. Trends Mol Med. 2008_x000D_ Dec;14(12):530-8._x000D_ _x000D_ 5: Meng X, Yang B, Suen WC. Prospects for modulating the CD40/CD40L pathway in_x000D_ the therapy of the hyper-IgM syndrome. Innate Immun. 2018 Jan;24(1):4-10._x000D_ _x000D_ 6: Antoniades C, Bakogiannis C, Tousoulis D, Antonopoulos AS, Stefanadis C. The_x000D_ CD40/CD40 ligand system: linking inflammation with atherothrombosis. J Am Coll_x000D_ Cardiol. 2009 Aug 18;54(8):669-77._x000D_ _x000D_ 7: Danese S, Fiocchi C. Platelet activation and the CD40/CD40 ligand pathway:_x000D_ mechanisms and implications for human disease. Crit Rev Immunol._x000D_ 2005;25(2):103-21._x000D_ _x000D_ 8: Schönbeck U, Libby P. The CD40/CD154 receptor/ligand dyad. Cell Mol Life Sci._x000D_ 2001 Jan;58(1):4-43._x000D_ 9: Sahler J, Spinelli S, Phipps R, Blumberg N. CD40 ligand (CD154) involvement_x000D_ in platelet transfusion reactions. Transfus Clin Biol. 2012 Jun;19(3):98-103._x000D_ _x000D_ Products Related to CD40 Ligand (Human, Recombinant) : Proteins

• Short Description:

  Catalog Number: B2010347 (10 ug)_x000D_ CD40 Ligand (Human, Recombinant) is a high quality research product used as highly pure CD40 Ligand (Human, Recombinant) expressed in E. coli. This protein acts as an important role in immune system regulation, including myeloid progenitor cell development. Custom bulk orders of this product are available upon request.

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3