CD40 Ligand (Human, Recombinant)

CAT: 0952-B2010347Size: 10 µgDry Ice: NoHazardous: No
CAT#:0952-B2010347Size:10 µg
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Description
CD40 Ligand (Human, Recombinant)_x000D_ Catalog number: B2010347_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Volume/Weight: 10 ug_x000D_ pH: 7.4 upon reconstitution_x000D_ Supplied as: Lyophilized Powder_x000D_ Appearance: Powder_x000D_ Applications: highly pure CD40 Ligand (Human, Recombinant) expressed in E. coli. This protein acts as an important role in immune system regulation, including myeloid progenitor cell development._x000D_ Storage: -20C_x000D_ Keywords: rHuCD40L; CD154; TRAP; TNFSF5; CD40LG; CD40-L_x000D_ Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Kuhn NF, Purdon TJ, van Leeuwen DG, Lopez AV, Curran KJ, Daniyan AF,_x000D_ Brentjens RJ. CD40_Ligand-Modified Chimeric Antigen Receptor T Cells Enhance_x000D_ Antitumor Function by Eliciting an Endogenous Antitumor Response. Cancer Cell._x000D_ 2019 Mar 18;35(3):473-488.e6._x000D_ _x000D_ 2: Karnell JL, Rieder SA, Ettinger R, Kolbeck R. Targeting the CD40-CD40L_x000D_ pathway in autoimmune diseases: Humoral immunity and beyond. Adv Drug Deliv Rev._x000D_ 2019 Feb 15;141:92-103._x000D_ _x000D_ 3: Kawabe T, Matsushima M, Hashimoto N, Imaizumi K, Hasegawa Y. CD40/CD40_ligand_x000D_ interactions in immune responses and pulmonary immunity. Nagoya J Med Sci. 2011_x000D_ Aug;73(3-4):69-78._x000D_ _x000D_ 4: Rizvi M, Pathak D, Freedman JE, Chakrabarti S. CD40-CD40_ligand interactions_x000D_ in oxidative stress, inflammation and vascular disease. Trends Mol Med. 2008_x000D_ Dec;14(12):530-8._x000D_ _x000D_ 5: Meng X, Yang B, Suen WC. Prospects for modulating the CD40/CD40L pathway in_x000D_ the therapy of the hyper-IgM syndrome. Innate Immun. 2018 Jan;24(1):4-10._x000D_ _x000D_ 6: Antoniades C, Bakogiannis C, Tousoulis D, Antonopoulos AS, Stefanadis C. The_x000D_ CD40/CD40 ligand system: linking inflammation with atherothrombosis. J Am Coll_x000D_ Cardiol. 2009 Aug 18;54(8):669-77._x000D_ _x000D_ 7: Danese S, Fiocchi C. Platelet activation and the CD40/CD40 ligand pathway:_x000D_ mechanisms and implications for human disease. Crit Rev Immunol._x000D_ 2005;25(2):103-21._x000D_ _x000D_ 8: Schönbeck U, Libby P. The CD40/CD154 receptor/ligand dyad. Cell Mol Life Sci._x000D_ 2001 Jan;58(1):4-43._x000D_ 9: Sahler J, Spinelli S, Phipps R, Blumberg N. CD40 ligand (CD154) involvement_x000D_ in platelet transfusion reactions. Transfus Clin Biol. 2012 Jun;19(3):98-103._x000D_ _x000D_ Products Related to CD40 Ligand (Human, Recombinant) : Proteins
CAS Number
9000-83-3
Short Description
Catalog Number: B2010347 (10 ug)
Weight
0.15
Length
2
Width
0.5
Height
0.5

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