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Blonanserin

CAT: 0804-HY-13575-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-13575-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Blonanserin (AD-5423) is a potent and orally active 5-HT2A (Ki=0.812 nM) and dopamine D2 receptor (Ki =0.142 nM) antagonist. Blonanserin is usually acts as an atypical antipsychotic agent and can be used for the research of extrapyramidal symptoms, excessive sedation, or hypotension[1].
CAS Number
132810-10-7
Product Name Alternative
AD-5423
UNSPSC
12352005
Hazard Statement
H302
Target
5-HT Receptor; Adrenergic Receptor; Dopamine Receptor; Sigma Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Blonanserin.html
Purity
99.62
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
FC1=CC=C(C2=C(CCCCCC3)C3=NC(N4CCN(CC)CC4)=C2)C=C1
Molecular Formula
C23H30FN3
Molecular Weight
367.50
Precautions
H302
References & Citations
[1]Blonanserin|[2]Saori Takeuchi, et al. Blonanserin ameliorates social deficit through dopamine-D 3 receptor antagonism in mice administered phencyclidine as an animal model of schizophrenia. Neurochem Int. 2019 Sep;128:127-134.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
5-HT2 Receptor; D1 Receptor; D2 Receptor; D3 Receptor; D4 Receptor; MUC2; α adrenergic receptor; α-1 microglobulin

Alternative Products

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MBS3601308-01Blonanserin
HFA81184-01Blonanserin C

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