Products for Research Use Only
RegisterLogin

Ropivacaine

CAT: 0804-HY-B0563-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B0563-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Ropivacain is a potent sodium channel blocker. Ropivacain blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese[1][2]. Ropivacaine is also an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane[3]. Ropivacaine is used for the research of neuropathic pain management[1].
CAS Number
84057-95-4
UNSPSC
12352005
Hazard Statement
H302
Target
Potassium Channel; Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/ropivacaine.html
Purity
99.98
Solubility
DMSO : 12.5 mg/mL (ultrasonic)
Smiles
O=C([C@H]1N(CCC)CCCC1)NC2=C(C)C=CC=C2C
Molecular Formula
C17H26N2O
Molecular Weight
274.40
Precautions
H302
References & Citations
[1]Li TF, et al. Epidural sustained release ropivacaine prolongs anti-allodynia and anti-hyperalgesia in developing and established neuropathic pain. PLoS One. 2015 Jan 24;10 (1) :e0117321.|[2]Milan Patel, et al. Ropivacaine Inhibits Pressure-Induced Lung Endothelial Hyperpermeability in Models of Acute Hypertension. Life Sci. 2019 Apr 1;222:22-28.|[3]Dene Simpson, et al. Ropivacaine: a review of its use in regional anaesthesia and acute pain management. Drugs. 2005;65 (18) :2675-717.|[4]Hye Won Shin, et al. The inhibitory effects of bupivacaine, levobupivacaine, and ropivacaine on K2P (two-pore domain potassium) channel TREK-1. J Anesth
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
In Vitro Cell Dev Biol Anim. 2024 Oct;60 (9) :1109-1120.|Int J Neuropsychopharmacol. 2025 Oct 1;28 (10) :pyaf066.|J Toxicol Sci. 2023;48 (3) :139-148.|BMC Pregnancy Childbirth. 2025 Jun 2;25 (1) :646.|Eur Spine J. 2022 Nov;31 (11) :2960-2971.|J Exp Clin Cancer Res. 2024 Mar 25;43 (1) :90.|Stem Cell Res Ther. 2021 Feb 4;12 (1) :107.

Alternative Products

CatalogName
BA6868-50Ropivacaine
FR65151-01Ropivacaine HCl
TMID-0185-01(±) -Ropivacaine-d7
T61475-01Ropivacaine mesylate
sc-472719(S) -Ropivacaine
A17663-50Ropivacaine 50mg
90028387-01Ropivacaine hydrochloride

Popular Products