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DN02

CAT: 0804-HY-148116-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-148116-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DN02 is a potent, selective BRD8 bromodomain probe. DN02 has exhibits high affinity for the BRD8 (1) (Ki=32 nM), which is 30-fold more affinity than BRD8 (2) (Ki > 1000 nM) [1].
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dn02.html
Purity
98.19
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1N(C)C=C(C2=C(OC)C=C(CN3CC(N)C3)C=C2OC)C4=C1C=C(F)C=C4
Molecular Formula
C22H24FN3O3
Molecular Weight
397.44
References & Citations
[1]Remillard D, et, al. Chemoproteomics Enabled Discovery of Selective Probes for NuA4 Factor BRD8. ACS Chem Biol. 2021 Nov 19;16 (11) :2185-2192.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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