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Moclobemide

CAT: 0804-HY-B0534-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0534-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Moclobemide (Ro111163) is a brain-penetrant and reversible monoamine oxidase (MAO-A) inhibitor with an IC50 of 6.061 μM for hMAO-A[1].Moclobemide up-regulates proliferation of hippocampal progenitor cells in chronically stressed mice.
CAS Number
71320-77-9
Product Name Alternative
Ro111163
UNSPSC
12352005
Hazard Statement
H302, H315, H318, H335
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Moclobemide.html
Purity
99.12
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NCCN1CCOCC1)C2=CC=C(Cl)C=C2
Molecular Formula
C13H17ClN2O2
Molecular Weight
268.74
Precautions
H302, H315, H318, H335
References & Citations
[1]Nafiz Öncü Can, et al. Synthesis of New Hydrazone Derivatives for MAO Enzymes Inhibitory Activity. Molecules. 2017 Aug 20;22 (8) :1381.|[2]Yun-feng Li, et al. Moclobemide up-regulates proliferation of hippocampal progenitor cells in chronically stressed mice. Acta Pharmacol Sin. 2004 Nov;25 (11) :1408-12.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
MAO-A

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A11885-25Moclobemide 25mg
A11885-50Moclobemide 50mg
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A11885-5Moclobemide 5mg
A11885-100Moclobemide 100mg

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