21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione

21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione

• CAS Number: 37413-91-5
• UNSPSC Description: 21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione is an intermediate of delta 9,11 steroids synthesis, for example, Vamorolone?(HY-109017). The delta 9,11 steroids are modifications of glucocorticoids and has anti-inflammatory properties. The delta 9,11 steroids are agents for protection against cell damage (lipid peroxidation) and inhibition of neovascularization[1].
• Target Antigen: Glucocorticoid Receptor; NF-κB
• Type: Reference compound
• Related Pathways: Immunology/Inflammation;NF-κB;Vitamin D Related/Nuclear Receptor
• Field of Research: Metabolic Disease; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/21-acetoxypregna-1-4-9-11-16-tetraene-3-20-dione.html
• Smiles: C[C@@]12[C@](CC=C2C(COC(C)=O)=O)([H])[C@@]3([H])C([C@@]4(C(CC3)=CC(C=C4)=O)C)=CC1
• Molecular Weight: 366.45
• References & Citations: [1]Erica K M Reeves, et al. VBP15: preclinical characterization of a novel anti-inflammatory delta 9,11 steroid. Bioorg Med Chem
• Shipping Conditions: Room Temperature