Recombinant Mouse ARG1 Protein(Gst Tag)
CAT:
763-PDEM100157-02
Size:
20 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Recombinant Mouse ARG1 Protein(Gst Tag)
- Background: Arginase is the focal enzyme of the urea cycle hydrolysing L-arginine to urea and L-ornithine. Emerging studies have identified arginase in the vasculature and have implicated this enzyme in the regulation of nitric oxide (NO) synthesis and the development of vascular disease. Arginase also redirects the metabolism of L-arginine to L-ornithine and the formation of polyamines and L-proline, which are essential for smooth muscle cell growth and collagen synthesis. Arginase is encoded by two recently discovered genes (Arginase I and Arginase II). In most mammals, Arginase 1 (ARG1) also known as Arginase, liver, which functions in the urea cycle, and is located primarily in the cytoplasm of the liver. The second isozyme, Arginase II, has been implicated in the regulation of the arginine/ornithine concentrations in the cell. It is located in mitochondria of several tissues in the body, with most abundance in the kidney and prostate. It may be found at lower levels in macrophages, lactating mammary glands, and brain.
- Abbreviation: ARG1
- Synonyms: ARG, Arginase, Liver Arginase, Arginase-1, Arg1, Arginase I, Liver-type arginase, Type I arginase, Arg1, Arginase-1, Liver-type arginase, Type I arginase
- CAS Number: 9000-83-3
- UniProt: Q61176
- Accession Number: Q61176
- Host: E. coli
- Origin Species: Mouse
- Tag: N-Gst
- Sequence: Met1-Lys322
- Purity: > 90% as determined by reducing SDS-PAGE.
- Bioactivity: Not validated for activity
- Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
- Molecular Weight: 60 kDa
- Shipping Conditions: This product is provided as lyophilized powder which is shipped with ice packs.
- Storage Conditions: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.