JNJ-42153605
CAT:
804-HY-18162-03
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
JNJ-42153605
- CAS Number: 1254977-87-1
- UNSPSC Description: JNJ-42153605 is a positive allosteric modulator of the metabotropic glutamate 2 (mGlu2) receptor with an EC50 of 17 nM.
- Target Antigen: mGluR
- Type: Reference compound
- Related Pathways: GPCR/G Protein;Neuronal Signaling
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/JNJ-42153605.html
- Solubility: DMSO : 16.67 mg/mL (ultrasonic)
- Smiles: FC(C1=C(N2CCC(C3=CC=CC=C3)CC2)C=CN4C1=NN=C4CC5CC5)(F)F
- Molecular Weight: 400.44
- References & Citations: [1]Cid JM, et al. Discovery of 3-cyclopropylmethyl-7-(4-phenylpiperidin-1-yl)-8-trifluoromethyl[1,2,4]triazolo[4,3-a]pyridine (JNJ-42153605): a positive allosteric modulator of the metabotropic glutamate 2 receptor. J Med Chem. 2012 Oct 25;55(20):8770-89.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported