α-Bulnesene

• Description :

  α-Bulnesene is a novel PAF receptor antagonist with the IC50 of 17.62 μM. α-Bulnesene can be isolated from Pogostemon cablin. α-Bulnesene shows inhibitory effect on platelet-activating factor and arachidonic acid induced rabbit platelet aggregation[1].

• UNSPSC :

  12352211

• Target :

  Platelet-activating Factor Receptor (PAFR)

• Type :

  Natural Products

• Related Pathways :

  GPCR/G Protein

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/α-bulnesene.html

• Purity :

  94.17

• Solubility :

  DMSO : 10 mg/mL (ultrasonic; warming)

• Smiles :

  C[C@@H]1[C@@]2([H])C(CC1)=C(CC[C@H](C2)C(C)=C)C

• Molecular Formula :

  C15H24

• Molecular Weight :

  204.35

• References & Citations :

  [1]Hsu HC, et al. Alpha-bulnesene, a novel PAF receptor antagonist isolated from Pogostemon cablin. Biochem Biophys Res Commun. 2006;345 (3) :1033-1038.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light, stored under nitrogen)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [3691-11-0]