MuRF1-IN-2

• Description:

  MuRF1-IN-2 (Example 3) is a MuRF1 inhibitor. MuRF1-IN-2 can be used for research of muscle wasting conditions, of skeletal or cardial muscle atrophy[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Bacterial; E1/E2/E3 Enzyme

• Type:

  Reference compound

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/murf1-in-2.html

• Concentration:

  10mM

• Purity:

  99.05

• Solubility:

  DMSO : 11.67 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  O=C(OC(C)C(NC(NC)=O)=O)C1=CC=C(COC2=CC(O3)=C(C=C2)C(C)=CC3=O)C=C1

• Molecular Formula:

  C23H22N2O7

• Molecular Weight:

  438.43

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Adams, Volker, et al. Preparation of chromen-2-one compounds suitable for the treatment and prophylaxis of muscle wasting and other conditions. Patent. WO2021032643.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [937891-74-2]