PRMT7 Antibody

• Description:

  Arginine methylation is an irreversible protein modification catalyzed by Arginine methyltransferases, such as PRMT7, which uses S-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated in signal transduction, RNA transport and RNA splicing. PRMT7 has two methyltransferase domains, each containing a putative AdoMet-binding motif. The N-terminal methyltransferase domain closely resembles the catalytic core of PRMT5, and the C-terminal domain is most similar to that of PRMT1. Three PRMT7 splice variants have been identified by database analysis. PRMT7 is localized to the nucleus and cytoplasm and moderate expression is observed in adult brain and lung tissues.

• UniProt:

  Q9NVM4

• Host:

  Mouse

• Immunogen:

  Recombinant full-length human PRMT7 protein was used as the immunogen for the PRMT7 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG1

• Applications:

  WB

• Format:

  Purified

• Buffer:

  1 mg/ml in 1X PBS; BSA free, sodium azide free

• Reconstitution:

  Aliquot the PRMT7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This PRMT7 antibody is available for research use only.

• CAS Number:

  9007-83-4