MICA Antibody
CAT:
800-V9703-100UG
Size:
100 µg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
MICA Antibody
- Description: MICA and MICB are stress-induced antigens that are related to major histocompatibility complex (MHC) class I molecules. MICA and MICB are frequently expressed in epithelial tumors. These highly glycosylated cell surface proteins are stably expressed without conventional class I peptide ligands or association with -2-microglobulin. The expression is induced on proliferating or heat shock-stressed epithelial cells. MICA and MICB are broadly recognized by intestinal epithelial γδ T cells expressing variable TCRs, suggesting that these antigens may play a central role in the signaling of cellular distress to evoke immune responses in the intestinal epithelium.
- CAS Number: 9007-83-4
- UniProt: Q29983
- Host: Mouse
- Immunogen: A portion of amino acids 1-200 was used as the immunogen for the MICA antibody.
- Clonality: Monoclonal
- Isotype: IgG2b κ
- Applications: WB, IHC-P
- Format: Purified
- Buffer: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
- Reconstitution: Aliquot the MICA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
- Limitations: This MICA antibody is available for research use only.