Interleukin 15 Antibody / IL15

• Description:

  Interleukin-15 (IL-15), also designated IL-T, is a cloned cytokine which shares several biological activities but no sequence homology with IL-2. Human, mouse and simian IL-15 cDNA clones have been isolated and characterized. All 3 species encode a 162 amino acid residue precursor protein containing a 48 amino acid leader that is cleaved to generate the mature form of IL-15. IL-15 stimulates the proliferation of T cells and NK cells, while enhancing B cell expansion and antibody production. Unlike IL-2, IL-15 is not produced by lymphocytes, but appears to be produced by macrophages, epithelial lines, muscle and placenta. IL-15 has also been shown to be a chemoattractant for human blood T lymphocytes and to be able to induce lymphokine-activated killer (LAK) activity in NK cells as well as to be able to induce the generation of cytolytic effector cells. Studies have shown that IL-15 is the only other cytokine that shares the subunit.

• Specifications:

  Immunohistochemistry (FFPE) : 1-2 µg/mL

• UniProt:

  P40933

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  A recombinant protein fragment was used as the immunogen for the Interleukin 15 antibody.

• Clonality:

  Monoclonal

• Isotype:

  IgG1 k

• Clone:

  IL15/4353

• Applications:

  IHC-P

• Purity:

  Protein A/G affinity

• Format:

  Purified

• Buffer:

  1 mg/ml in 1X PBS; BSA free, sodium azide free

• Reconstitution:

  Aliquot the Interleukin 15 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

• Limitations:

  This Interleukin 15 antibody is available for research use only.

• Storage Conditions:

  Aliquot the Interleukin 15 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

• Formulation:

  1 mg/mL in 1X PBS; BSA free, sodium azide free

• Applications Notes:

  Optimal dilution of the Interleukin 15 antibody should be determined by the researcher.

• CAS Number:

  9007-83-4

• Location:

  Secreted, Cytoplasm, Nuclear

• Image Legend:

  IHC staining of FFPE human adrenal gland tissue with Interleukin 15 antibody (clone IL15/4353) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.