VLDLR Recombinant Antibody / VLDL Receptor

VLDLR Recombinant Antibody / VLDL Receptor

• Description: VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.
• CAS Number: 9000-83-3
• UniProt: P98155
• Host: Mouse
• Immunogen: A recombinant human protein fragment from the C-terminal region was used as the immunogen for the VLDLR antibody.
• Clonality: Monoclonal
• Isotype: IgG1 κ
• Type: Recombinant
• Applications: IHC-P
• Format: Purified
• Buffer: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Reconstitution: Aliquot the VLDLR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
• Limitations: This VLDLR antibody is available for research use only.